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Emulsification module

Price per piece
1-19 20-39 40-59 60+
 75.00  66.00  59.00  54.00

Aquamarijn offers microsieves optimized for emulsification with hydrophobic or hydrophilic coatings for making WATER in OIL or OIL in WATER emulsions respectively.

Watch a video of OIL in WATER emulsification
Watch a video of WATER in OIL emulsification

A dead-end module made of polyacetal and a cross-flow module made of PET (polyethylene terphthalate) are available. For emulsification with strong solvents, we offer a robust stainless steel module. Different designs & materials are available upon request.

 75.00

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Description

The microsieve membrane emulsification process generates monodisperse droplets by dispersing one fluid into a second, immiscible fluid through a precise microsieve. Thanks to the homogeneity of pore size, every droplet generated by the microsieve membrane is the same. In addition, hydrophobic or hydrophilic coatings for making WATER in OIL or OIL in WATER emulsions respectively, advances and stabilizes the process of emulsification. Altogether results in highly uniform, reproducible and size-controlled droplets (see video of droplet formation by microsieves ). The droplets can be transformed into particles after an appropriate solidification step.

In principle, the size of the droplet will be about 4 times larger than the width of the slit chip. It means:

o Slit chip 2×20 ⇒ ~ 8µm droplets

o Slit chip 3×30 ⇒ ~12µm droplets

o Slit chip 5×50 ⇒ ~25µm droplets

Additionally, membrane emulsification also can be performed with a low porosity membrane. In this case, the droplet size will be determined by the flow rate of the continuous flow. Contact us for technical support.

Microsieves Specification

Type
Shape
Inner diameter (µm)
Outer diameter
/length (µm)
Width (µm)
Pitch
Nozzles per chip
2x20Slit2029504
3x30Slit3034224
5x50Slit5051456

Stainless Steel module

Cross-flow solvent-resistant emulsification module

  • The module has 4 in/outlets that fit with standard coned 10-32 threaded connectors. The borosilicate glass window allows observation of the droplet formation with an optical microscope. The module consists of the main unit made of stainless steel, perfluoro elastomer O-ring, borosilicate top lid and PEEK Nano Tight Fittings, which altogether made the module fully solvent-resistant.
  • For fluid connections, Nano Tight fittings (4 items) and 1/16” OD PTFE tubing (2 meter) are provided.
  • The layout of all the channels is visible at the backside of the module:

DP1: Dispersed Phase inlet

DP2: Dispersed Phase outlet

CP1: Continuous Phase inlet as cross-flow inlet

CP2: Continuous Phase outlet as emulsion outlet

Slit chips can be 2×20; 3×30 or 5×50 (see specifications)

  • Accurate and stable flow for both the dispersed phase and continuous phase are important for the droplet formation process. Therefore, we recommend to use a syringe pump or a microfluidic flow controller to control the flow rate.

Dispersed Phase outlet DP2 is closed during emulsification by clamping the tubing. Cleaning of the module after the emulsification process is possible by rinsing the entire module with liquids (water or solvents) which dissolve the type of samples that were in contact with the module and are chemically compatible with the module. The backside of the chip can be cleaned after reopening DP2 by flowing water or solvents. The front side is accessible by opening the screw cap. Under all circumstances do not touch the chip surface and ensure a particle-free working environment to prevent damage or clogging of the membrane.

PET module

Cross-flow aqueous emulsification module (instruction video )

  • The cross-flow emulsification module is a great tool to study droplet formation as well as the membrane emulsification process. Microsieves are mounted in disc (29mm) which can be easily replaced for to work easily with different pore sizes for generations of different droplet sizes
  • The module has 4 in/outlets that fit with standard coned 10-32 threaded connectors. The plastic window allows observation of the droplet formation with an optical microscope. The module has a standard microscope slide size of 75 by 25 mm, which allows it to be fitted easily under a reflected light microscope. 
  • For fluid connections, Nano Tight fittings (4 items) wih 1/16” OD PTFE tubing (2 meter) OR Luer adapters (10-32 male to Luer Lock female, 4 items) are provided. The seals are made of nitrile rubber.
  • The layout of all the channels is visible at the backside of the module:

cross-flow holder

DP1: Dispersed Phase inlet

DP2: Dispersed Phase outlet

CP1: Continuous Phase inlet as cross-flow inlet

CP2: Continuous Phase outlet as emulsion outlet

2×20: indicating a type of slit chip. It can also be 3×30 or 5×50 (see specifications)

  • Accurate and stable flow for both the dispersed phase and continuous phase are important for the droplet formation process. Therefor, we recommend to use a syringe pump or a microfluidic flow controller to control the flow rate.

Dispersed Phase outlet DP2 is closed during emulsification by clamping the tubing. Cleaning of the module after the emulsification process is possible by rinsing the entire module with, for instance, water and/or isopropanol. The backside of the chip can be cleaned after reopening DP2 by flowing, for example, water or isopropanol. The front side is accessible by opening the screw cap. Under all circumstances do not touch the chip surface and ensure a particle-free working environment to prevent damage or clogging of the membrane.